2iiv
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2IIV is a | + | 2IIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIV OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:17055272</ref><references group="xtra"/> | |
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Single protein]] | ||
[[Category: Biftu, T.]] | [[Category: Biftu, T.]] | ||
[[Category: Scapin, G.]] | [[Category: Scapin, G.]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:25:13 2009'' |
Revision as of 13:25, 16 February 2009
Human dipeptidyl peptidase 4 in complex with a diazepan-2-one inhibitor
Template:ABSTRACT PUBMED 17055272
About this Structure
2IIV is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Scapin G, Patel S, Gao YD, Singh S, Wu J, Zhang X, Thornberry NA, Weber AE. (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoro ethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2007 Jan 1;17(1):49-52. Epub 2006 Oct 5. PMID:17055272 doi:10.1016/j.bmcl.2006.09.099
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