1wvj

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==About this Structure==
==About this Structure==
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1WVJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WVJ OCA].
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1WVJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WVJ OCA].
==Reference==
==Reference==
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Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP., Nielsen BB, Pickering DS, Greenwood JR, Brehm L, Gajhede M, Schousboe A, Kastrup JS, FEBS J. 2005 Apr;272(7):1639-48. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15794751 15794751]
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<ref group="xtra">PMID:15794751</ref><ref group="xtra">PMID:12215417</ref><ref group="xtra">PMID:11086992</ref><ref group="xtra">PMID:9865957</ref><references group="xtra"/>
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Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core., Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E, J Mol Biol. 2002 Sep 6;322(1):93-109. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12215417 12215417]
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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core., Armstrong N, Gouaux E, Neuron. 2000 Oct;28(1):165-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11086992 11086992]
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Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct., Chen GQ, Sun Y, Jin R, Gouaux E, Protein Sci. 1998 Dec;7(12):2623-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9865957 9865957]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
 
[[Category: Brehm, L.]]
[[Category: Brehm, L.]]
[[Category: Gajhede, M.]]
[[Category: Gajhede, M.]]
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[[Category: Ligand-binding core]]
[[Category: Ligand-binding core]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:00:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:57:49 2009''

Revision as of 13:57, 16 February 2009

Image:1wvj.png

Template:STRUCTURE 1wvj

Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP

Template:ABSTRACT PUBMED 15794751

About this Structure

1WVJ is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Nielsen BB, Pickering DS, Greenwood JR, Brehm L, Gajhede M, Schousboe A, Kastrup JS. Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP. FEBS J. 2005 Apr;272(7):1639-48. PMID:15794751 doi:10.1111/j.1742-4658.2005.04583.x
  • Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core. J Mol Biol. 2002 Sep 6;322(1):93-109. PMID:12215417
  • Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
  • Chen GQ, Sun Y, Jin R, Gouaux E. Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct. Protein Sci. 1998 Dec;7(12):2623-30. PMID:9865957

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