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1tu6

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==About this Structure==
==About this Structure==
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1TU6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU6 OCA].
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1TU6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU6 OCA].
==Reference==
==Reference==
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Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions., Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL, Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15341947 15341947]
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<ref group="xtra">PMID:15341947</ref><references group="xtra"/>
[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Barrett, D G.]]
[[Category: Barrett, D G.]]
[[Category: Catalano, J G.]]
[[Category: Catalano, J G.]]
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[[Category: Cysteine protease]]
[[Category: Cysteine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:30:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:21:34 2009''

Revision as of 14:21, 16 February 2009

Image:1tu6.png

Template:STRUCTURE 1tu6

Cathepsin K complexed with a ketoamide inhibitor

Template:ABSTRACT PUBMED 15341947

About this Structure

1TU6 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. PMID:15341947 doi:10.1016/j.bmcl.2004.07.031

Page seeded by OCA on Mon Feb 16 16:21:34 2009

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