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1t4e

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==About this Structure==
==About this Structure==
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1T4E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA].
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1T4E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA].
==Reference==
==Reference==
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Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells., Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF, J Med Chem. 2005 Feb 24;48(4):909-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15715460 15715460]
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<ref group="xtra">PMID:15715460</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Carver, T E.]]
[[Category: Carver, T E.]]
[[Category: Franks, C F.]]
[[Category: Franks, C F.]]
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[[Category: Mdm2-inhibitor complex]]
[[Category: Mdm2-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:11:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:54:35 2009''

Revision as of 14:54, 16 February 2009

Template:STRUCTURE 1t4e

Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor

Template:ABSTRACT PUBMED 15715460

About this Structure

1T4E is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF. Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells. J Med Chem. 2005 Feb 24;48(4):909-12. PMID:15715460 doi:10.1021/jm049137g

Page seeded by OCA on Mon Feb 16 16:54:35 2009

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