1y7c

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==Disease==
==Disease==
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Known disease associated with this structure: Erythremias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], HPFH, deletion type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Heinz body anemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Methemoglobinemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Sickle cell anemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Thalassemia-beta, dominant inclusion-body OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Thalassemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]]
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Known disease associated with this structure: Erythremias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Heinz body anemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Hereditary persistence of fetal hemoglobin OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Methemoglobinemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Sickle cell anemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Thalassemia-beta, dominant inclusion-body OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]], Thalassemias, beta- OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=141900 141900]]
==About this Structure==
==About this Structure==
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1Y7C is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y7C OCA].
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1Y7C is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y7C OCA].
==Reference==
==Reference==
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Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions., Kavanaugh JS, Rogers PH, Arnone A, Biochemistry. 2005 Apr 26;44(16):6101-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15835899 15835899]
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<ref group="xtra">PMID:15835899</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Arnone, A.]]
[[Category: Arnone, A.]]
[[Category: Kavanaugh, J S.]]
[[Category: Kavanaugh, J S.]]
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[[Category: Hemoglobin mutant]]
[[Category: Hemoglobin mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:28:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:09:03 2009''

Revision as of 15:09, 16 February 2009

Template:STRUCTURE 1y7c

Contents

T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set)

Template:ABSTRACT PUBMED 15835899

Disease

Known disease associated with this structure: Erythremias, beta- OMIM:[141900], Heinz body anemias, beta- OMIM:[141900], Hereditary persistence of fetal hemoglobin OMIM:[141900], Methemoglobinemias, beta- OMIM:[141900], Sickle cell anemia OMIM:[141900], Thalassemia-beta, dominant inclusion-body OMIM:[141900], Thalassemias, beta- OMIM:[141900]

About this Structure

1Y7C is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kavanaugh JS, Rogers PH, Arnone A. Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry. 2005 Apr 26;44(16):6101-21. PMID:15835899 doi:http://dx.doi.org/10.1021/bi047813a

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