1xg6

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==About this Structure==
==About this Structure==
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1XG6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XG6 OCA].
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1XG6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XG6 OCA].
==Reference==
==Reference==
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Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis., Khamrui S, Dasgupta J, Dattagupta JK, Sen U, Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16081330 16081330]
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<ref group="xtra">PMID:16081330</ref><ref group="xtra">PMID:10328267</ref><ref group="xtra">PMID:11438758</ref><references group="xtra"/>
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Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site., Dattagupta JK, Podder A, Chakrabarti C, Sen U, Mukhopadhyay D, Dutta SK, Singh M, Proteins. 1999 May 15;35(3):321-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10328267 10328267]
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The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14--&gt;Lys and Asn14--&gt;Asp., Ravichandran S, Dasgupta J, Chakrabarti C, Ghosh S, Singh M, Dattagupta JK, Protein Eng. 2001 May;14(5):349-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11438758 11438758]
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[[Category: Psophocarpus tetragonolobus]]
[[Category: Psophocarpus tetragonolobus]]
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[[Category: Single protein]]
 
[[Category: Dasgupta, J.]]
[[Category: Dasgupta, J.]]
[[Category: Dattagupta, J K.]]
[[Category: Dattagupta, J K.]]
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[[Category: Trypsin inhibitor]]
[[Category: Trypsin inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:15:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:47:13 2009''

Revision as of 15:47, 16 February 2009

Image:1xg6.png

Template:STRUCTURE 1xg6

The crystal structure of the P1 mutant (Leu to Arg)of a Winged bean chymotrypsin inhibitor(Kunitz)solved at 2.15A resolution

Template:ABSTRACT PUBMED 16081330

About this Structure

1XG6 is a 1 chain structure of sequence from Psophocarpus tetragonolobus. Full crystallographic information is available from OCA.

Reference

  • Khamrui S, Dasgupta J, Dattagupta JK, Sen U. Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis. Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:16081330 doi:10.1016/j.bbapap.2005.06.012
  • Dattagupta JK, Podder A, Chakrabarti C, Sen U, Mukhopadhyay D, Dutta SK, Singh M. Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site. Proteins. 1999 May 15;35(3):321-31. PMID:10328267
  • Ravichandran S, Dasgupta J, Chakrabarti C, Ghosh S, Singh M, Dattagupta JK. The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp. Protein Eng. 2001 May;14(5):349-57. PMID:11438758

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