This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2anq
From Proteopedia
(Difference between revisions)
| Line 20: | Line 20: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2ANQ is a | + | 2ANQ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:17125251</ref><references group="xtra"/> | |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Brown, E D.]] | [[Category: Brown, E D.]] | ||
[[Category: Daigle, D M.]] | [[Category: Daigle, D M.]] | ||
| Line 38: | Line 37: | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:25:12 2009'' |
Revision as of 16:25, 16 February 2009
Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.
Template:ABSTRACT PUBMED 17125251
About this Structure
2ANQ is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v
Page seeded by OCA on Mon Feb 16 18:25:12 2009
