2vki

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==About this Structure==
==About this Structure==
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2VKI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKI OCA].
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2VKI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKI OCA].
==Reference==
==Reference==
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Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance., Bayascas JR, Wullschleger S, Sakamoto K, Garcia-Martinez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR, Mol Cell Biol. 2008 May;28(10):3258-72. Epub 2008 Mar 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18347057 18347057]
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<ref group="xtra">PMID:18347057</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
 
[[Category: Aalten, D M.F Van.]]
[[Category: Aalten, D M.F Van.]]
[[Category: Alessi, D R.]]
[[Category: Alessi, D R.]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:13:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:54:36 2009''

Revision as of 16:54, 16 February 2009

Image:2vki.png

Template:STRUCTURE 2vki

STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT

Template:ABSTRACT PUBMED 18347057

About this Structure

2VKI is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bayascas JR, Wullschleger S, Sakamoto K, Garcia-Martinez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol. 2008 May;28(10):3258-72. Epub 2008 Mar 17. PMID:18347057 doi:10.1128/MCB.02032-07

Page seeded by OCA on Mon Feb 16 18:54:36 2009

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