1yy9

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==About this Structure==
==About this Structure==
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1YY9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus/homo_sapiens Mus musculus/homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA].
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1YY9 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus/homo_sapiens Mus musculus/homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA].
==Reference==
==Reference==
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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab., Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM, Cancer Cell. 2005 Apr;7(4):301-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15837620 15837620]
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<ref group="xtra">PMID:15837620</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus/homo sapiens]]
[[Category: Mus musculus/homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Ferguson, K M.]]
[[Category: Ferguson, K M.]]
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[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:39:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:30:08 2009''

Revision as of 17:30, 16 February 2009

Template:STRUCTURE 1yy9

Contents

Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225

Template:ABSTRACT PUBMED 15837620

Disease

Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this Structure

1YY9 is a 3 chains structure of sequences from Homo sapiens and Mus musculus/homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003

Page seeded by OCA on Mon Feb 16 19:30:08 2009

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