2fdp

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==About this Structure==
==About this Structure==
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2FDP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA].
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2FDP is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA].
==Reference==
==Reference==
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Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1., Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD, J Med Chem. 2006 Feb 9;49(3):839-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16451048 16451048]
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<ref group="xtra">PMID:16451048</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Single protein]]
 
[[Category: Ballinger, M D.]]
[[Category: Ballinger, M D.]]
[[Category: Fucini, R V.]]
[[Category: Fucini, R V.]]
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[[Category: Bace]]
[[Category: Bace]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:59:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:47:53 2009''

Revision as of 18:47, 16 February 2009

Image:2fdp.png

Template:STRUCTURE 2fdp

Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor

Template:ABSTRACT PUBMED 16451048

About this Structure

2FDP is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. J Med Chem. 2006 Feb 9;49(3):839-42. PMID:16451048 doi:10.1021/jm0509142

Page seeded by OCA on Mon Feb 16 20:47:53 2009

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