2gq2

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==About this Structure==
==About this Structure==
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2GQ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ2 OCA].
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2GQ2 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ2 OCA].
==Reference==
==Reference==
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NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design., Sampathkumar P, Turley S, Sibley CH, Hol WG, J Mol Biol. 2006 Jun 30;360(1):1-6. Epub 2006 May 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16730023 16730023]
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<ref group="xtra">PMID:16730023</ref><ref group="xtra">PMID:16139296</ref><references group="xtra"/>
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Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution., Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG, J Mol Biol. 2005 Oct 7;352(5):1091-104. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16139296 16139296]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
 
[[Category: Hol, W G.]]
[[Category: Hol, W G.]]
[[Category: Sampathkumar, P.]]
[[Category: Sampathkumar, P.]]
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[[Category: Tscp]]
[[Category: Tscp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:25:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:26:59 2009''

Revision as of 20:27, 16 February 2009

Template:STRUCTURE 2gq2

Mycobacterium tuberculosis ThyX-NADP complex

Template:ABSTRACT PUBMED 16730023

About this Structure

2GQ2 is a 4 chains structure of sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Sampathkumar P, Turley S, Sibley CH, Hol WG. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J Mol Biol. 2006 Jun 30;360(1):1-6. Epub 2006 May 12. PMID:16730023 doi:10.1016/j.jmb.2006.04.061
  • Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. J Mol Biol. 2005 Oct 7;352(5):1091-104. PMID:16139296 doi:10.1016/j.jmb.2005.07.071

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