1t32

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==About this Structure==
==About this Structure==
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1T32 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T32 OCA].
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1T32 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T32 OCA].
==Reference==
==Reference==
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A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo., de Garavilla L, Greco MN, Sukumar N, Chen ZW, Pineda AO, Mathews FS, Di Cera E, Giardino EC, Wells GI, Haertlein BJ, Kauffman JA, Corcoran TW, Derian CK, Eckardt AJ, Damiano BP, Andrade-Gordon P, Maryanoff BE, J Biol Chem. 2005 May 6;280(18):18001-7. Epub 2005 Feb 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15741158 15741158]
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<ref group="xtra">PMID:15741158</ref><ref group="xtra">PMID:8896442</ref><references group="xtra"/>
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The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities., Hof P, Mayr I, Huber R, Korzus E, Potempa J, Travis J, Powers JC, Bode W, EMBO J. 1996 Oct 15;15(20):5481-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8896442 8896442]
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[[Category: Cathepsin G]]
[[Category: Cathepsin G]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Abraham, W M.]]
[[Category: Abraham, W M.]]
[[Category: Andrade-Gordon, P.]]
[[Category: Andrade-Gordon, P.]]
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[[Category: Inflammation inhibitor serine protease]]
[[Category: Inflammation inhibitor serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:47:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:27:53 2009''

Revision as of 21:28, 16 February 2009

Image:1t32.png

Template:STRUCTURE 1t32

A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation

Template:ABSTRACT PUBMED 15741158

About this Structure

1T32 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • de Garavilla L, Greco MN, Sukumar N, Chen ZW, Pineda AO, Mathews FS, Di Cera E, Giardino EC, Wells GI, Haertlein BJ, Kauffman JA, Corcoran TW, Derian CK, Eckardt AJ, Damiano BP, Andrade-Gordon P, Maryanoff BE. A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J Biol Chem. 2005 May 6;280(18):18001-7. Epub 2005 Feb 28. PMID:15741158 doi:10.1074/jbc.M501302200
  • Hof P, Mayr I, Huber R, Korzus E, Potempa J, Travis J, Powers JC, Bode W. The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities. EMBO J. 1996 Oct 15;15(20):5481-91. PMID:8896442

Page seeded by OCA on Mon Feb 16 23:27:53 2009

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