1ghv
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 1GHV is a | + | 1GHV is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHV OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:11292354</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Protein complex]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Elrod, K.]] | [[Category: Elrod, K.]] | ||
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[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:47:17 2009'' |
Revision as of 21:47, 16 February 2009
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Template:ABSTRACT PUBMED 11292354
About this Structure
1GHV is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354 doi:http://dx.doi.org/10.1006/jmbi.2001.4516
Page seeded by OCA on Mon Feb 16 23:47:17 2009
Categories: Homo sapiens | Thrombin | Elrod, K. | Hatayte, J. | Janc, J. | Katz, B A. | Link, J. | Litvak, J. | Luong, C. | Mackman, R L. | Rai, R. | Rice, K. | Rice, M. | Sideris, S. | Spencer, J. | Sprengeler, P A. | Verner, E. | Young, W. | Oxyanion hole water | Shift of pka of his57 | Specificity | Structure-based drug design | Three-centered | Trypsin | Urokinase | Very short hydrogen bond | Zn+2-mediated inhibition