2fxm

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==About this Structure==
==About this Structure==
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2FXM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXM OCA].
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2FXM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXM OCA].
==Reference==
==Reference==
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Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment., Blankenfeldt W, Thoma NH, Wray JS, Gautel M, Schlichting I, Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17713-7. Epub 2006 Nov 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17095604 17095604]
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<ref group="xtra">PMID:17095604</ref><ref group="xtra">PMID:10024460</ref><ref group="xtra">PMID:12867988</ref><references group="xtra"/>
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Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C., Gruen M, Gautel M, J Mol Biol. 1999 Feb 26;286(3):933-49. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10024460 10024460]
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Visualization of an unstable coiled coil from the scallop myosin rod., Li Y, Brown JH, Reshetnikova L, Blazsek A, Farkas L, Nyitray L, Cohen C, Nature. 2003 Jul 17;424(6946):341-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12867988 12867988]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Blankenfeldt, W.]]
[[Category: Blankenfeldt, W.]]
[[Category: Gautel, M.]]
[[Category: Gautel, M.]]
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[[Category: Thick filament]]
[[Category: Thick filament]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:15:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:55:12 2009''

Revision as of 21:55, 16 February 2009

Image:2fxm.png

Template:STRUCTURE 2fxm

Structure of the human beta-myosin S2 fragment

Template:ABSTRACT PUBMED 17095604

About this Structure

2FXM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Blankenfeldt W, Thoma NH, Wray JS, Gautel M, Schlichting I. Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17713-7. Epub 2006 Nov 9. PMID:17095604
  • Gruen M, Gautel M. Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C. J Mol Biol. 1999 Feb 26;286(3):933-49. PMID:10024460 doi:http://dx.doi.org/10.1006/jmbi.1998.2522
  • Li Y, Brown JH, Reshetnikova L, Blazsek A, Farkas L, Nyitray L, Cohen C. Visualization of an unstable coiled coil from the scallop myosin rod. Nature. 2003 Jul 17;424(6946):341-5. PMID:12867988 doi:http://dx.doi.org/10.1038/nature01801

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