2vx0

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==About this Structure==
==About this Structure==
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2VX0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX0 OCA].
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2VX0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX0 OCA].
==Reference==
==Reference==
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Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines., Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ, Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18434142 18434142]
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<ref group="xtra">PMID:18434142</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
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[[Category: Barratt, D.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Brassington, C A.]]
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[[Category: Green, I.]]
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[[Category: Kettle, J G.]]
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[[Category: Leach, A G.]]
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[[Category: Mccall, E J.]]
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[[Category: Read, J.]]
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[[Category: Valentine, A L.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
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[[Category: Unphosphorylated]]
[[Category: Unphosphorylated]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 20:36:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:56:58 2009''

Revision as of 21:57, 16 February 2009

Image:2vx0.png

Template:STRUCTURE 2vx0

EPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18434142

About this Structure

2VX0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015

Page seeded by OCA on Mon Feb 16 23:56:58 2009

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