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1s8o

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==About this Structure==
==About this Structure==
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1S8O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].
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1S8O is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].
==Reference==
==Reference==
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Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15096040 15096040]
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<ref group="xtra">PMID:15096040</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Microsomal epoxide hydrolase]]
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[[Category: Single protein]]
 
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
[[Category: Gomez, G A.]]
[[Category: Gomez, G A.]]
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[[Category: Domain-swapped dimer]]
[[Category: Domain-swapped dimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:37:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:11:30 2009''

Revision as of 22:11, 16 February 2009

Image:1s8o.png


PDB ID 1s8o

Drag the structure with the mouse to rotate
1s8o, resolution 2.60Å ()
Ligands:
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

Human soluble Epoxide Hydrolase

Template:ABSTRACT PUBMED 15096040

Disease

Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[132811]

About this Structure

1S8O is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:15096040 doi:10.1021/bi036189j

Page seeded by OCA on Tue Feb 17 00:11:30 2009

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