2et2

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==About this Structure==
==About this Structure==
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2ET2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET2 OCA].
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2ET2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET2 OCA].
==Reference==
==Reference==
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Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants., Dasgupta J, Khamrui S, Dattagupta JK, Sen U, Biochemistry. 2006 Jun 6;45(22):6783-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16734415 16734415]
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<ref group="xtra">PMID:16734415</ref><ref group="xtra">PMID:16081330</ref><ref group="xtra">PMID:12915726</ref><references group="xtra"/>
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Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis., Khamrui S, Dasgupta J, Dattagupta JK, Sen U, Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16081330 16081330]
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In silico mutations and molecular dynamics studies on a winged bean chymotrypsin inhibitor protein., Dasgupta J, Sen U, Dattagupta JK, Protein Eng. 2003 Jul;16(7):489-96. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12915726 12915726]
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[[Category: Psophocarpus tetragonolobus]]
[[Category: Psophocarpus tetragonolobus]]
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[[Category: Single protein]]
 
[[Category: Dasgupta, J.]]
[[Category: Dasgupta, J.]]
[[Category: Dattagupta, J K.]]
[[Category: Dattagupta, J K.]]
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[[Category: Scaffold]]
[[Category: Scaffold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:13:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:44:48 2009''

Revision as of 22:44, 16 February 2009

Image:2et2.png

Template:STRUCTURE 2et2

Crystal structure of an Asn to Ala mutant of Winged Bean Chymotrypsin Inhibitor protein

Template:ABSTRACT PUBMED 16734415

About this Structure

2ET2 is a 1 chain structure of sequence from Psophocarpus tetragonolobus. Full crystallographic information is available from OCA.

Reference

  • Dasgupta J, Khamrui S, Dattagupta JK, Sen U. Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants. Biochemistry. 2006 Jun 6;45(22):6783-92. PMID:16734415 doi:10.1021/bi060374q
  • Khamrui S, Dasgupta J, Dattagupta JK, Sen U. Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis. Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:16081330 doi:10.1016/j.bbapap.2005.06.012
  • Dasgupta J, Sen U, Dattagupta JK. In silico mutations and molecular dynamics studies on a winged bean chymotrypsin inhibitor protein. Protein Eng. 2003 Jul;16(7):489-96. PMID:12915726

Page seeded by OCA on Tue Feb 17 00:44:48 2009

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