1bzy

From Proteopedia

(Difference between revisions)

Revision as of 22:50, 16 February 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

Image:1bzy.png

1bzy, resolution 2.00Å ()

Ligands:

, ,

Activity:

Hypoxanthine phosphoribosyltransferase, with EC number 2.4.2.8

Structural annotation:
Resources:	CATH : 1Bzya00, 1Bzyb00, 1Bzyc00, 1Bzyd00 InterPro : Ipr005904, Ipr002375, Ipr000836 Pfam : PF00156 SCOP : d1bzya_, d1bzyb_, d1bzyc_, d1bzyd_ UniProt : P00492

Functional annotation:
Cellular component:	cytoplasm
Biological process:	purine nucleotide biosynthetic process purine ribonucleoside salvage nucleoside metabolic process hypoxanthine metabolic process protein homotetramerization behavior positive regulation of dopamine metabolic process
Molecular function:	transferase activity, transferring glycosyl groups hypoxanthine phosphoribosyltransferase activity protein binding protein homodimerization activity transferase activity magnesium ion binding metal ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR

Template:ABSTRACT PUBMED 10360366

About this Structure

1BZY is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Shi W, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor. Nat Struct Biol. 1999 Jun;6(6):588-93. PMID:10360366 doi:http://dx.doi.org/10.1038/9376

Page seeded by OCA on Tue Feb 17 00:50:08 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1bzy"

@@ Line 20: / Line 20: @@
 ==About this Structure==
-BZY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BZY OCA].
+BZY is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BZY OCA].
 ==Reference==
-The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor., Shi W, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC, Nat Struct Biol. 1999 Jun;6(6):588-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10360366 10360366]
+<ref group="xtra">PMID:10360366</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Hypoxanthine phosphoribosyltransferase]]
-[[Category: Single protein]]
 [[Category: Almo, S C.]]
 [[Category: Furneaux, R H.]]
@@ Line 44: / Line 43: @@
 [[Category: Transition state]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:01:00 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:50:08 2009''

1bzy

From Proteopedia

Revision as of 22:50, 16 February 2009

HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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