2pl0

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==About this Structure==
==About this Structure==
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2PL0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL0 OCA].
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2PL0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL0 OCA].
==Reference==
==Reference==
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Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex., Jacobs MD, Caron PR, Hare BJ, Proteins. 2007 Oct 1;70(4):1451-1460. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17910071 17910071]
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<ref group="xtra">PMID:17910071</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Single protein]]
 
[[Category: Jacobs, M D.]]
[[Category: Jacobs, M D.]]
[[Category: Kinase phosphorylation]]
[[Category: Kinase phosphorylation]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:09:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:23:36 2009''

Revision as of 00:23, 17 February 2009

Template:STRUCTURE 2pl0

Contents

LCK bound to imatinib

Template:ABSTRACT PUBMED 17910071

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

2PL0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jacobs MD, Caron PR, Hare BJ. Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex. Proteins. 2007 Oct 1;70(4):1451-1460. PMID:17910071 doi:10.1002/prot.21633

Page seeded by OCA on Tue Feb 17 02:23:36 2009

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