2ien

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==About this Structure==
==About this Structure==
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2IEN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1s6g 1s6g]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEN OCA].
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2IEN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1s6g 1s6g]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEN OCA].
==Reference==
==Reference==
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High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains., Tie Y, Boross PI, Wang YF, Gaddis L, Hussain AK, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2004 Apr 23;338(2):341-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15066436 15066436]
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<ref group="xtra">PMID:15066436</ref><ref group="xtra">PMID:14506019</ref><references group="xtra"/>
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Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro., Koh Y, Nakata H, Maeda K, Ogata H, Bilcer G, Devasamudram T, Kincaid JF, Boross P, Wang YF, Tie Y, Volarath P, Gaddis L, Harrison RW, Weber IT, Ghosh AK, Mitsuya H, Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14506019 14506019]
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[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Single protein]]
 
[[Category: Boross, P I.]]
[[Category: Boross, P I.]]
[[Category: Gaddis, L.]]
[[Category: Gaddis, L.]]
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[[Category: Uic-94017]]
[[Category: Uic-94017]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:36:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:16:40 2009''

Revision as of 03:16, 17 February 2009

Template:STRUCTURE 2ien

Crystal structure analysis of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017)

Template:ABSTRACT PUBMED 15066436

About this Structure

2IEN is a 2 chains structure of sequences from Human immunodeficiency virus 1. This structure supersedes the now removed PDB entry 1s6g. Full crystallographic information is available from OCA.

Reference

  • Tie Y, Boross PI, Wang YF, Gaddis L, Hussain AK, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52. PMID:15066436 doi:10.1016/j.jmb.2004.02.052
  • Koh Y, Nakata H, Maeda K, Ogata H, Bilcer G, Devasamudram T, Kincaid JF, Boross P, Wang YF, Tie Y, Volarath P, Gaddis L, Harrison RW, Weber IT, Ghosh AK, Mitsuya H. Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9. PMID:14506019

Page seeded by OCA on Tue Feb 17 05:16:40 2009

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