2a4l

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==About this Structure==
==About this Structure==
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2A4L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4L OCA].
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2A4L is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4L OCA].
==Reference==
==Reference==
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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine., De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH, Eur J Biochem. 1997 Jan 15;243(1-2):518-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9030780 9030780]
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<ref group="xtra">PMID:9030780</ref><ref group="xtra">PMID:8610110</ref><ref group="xtra">PMID:8510751</ref><references group="xtra"/>
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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase., De Azevedo WF Jr, Mueller-Dieckmann HJ, Schulze-Gahmen U, Worland PJ, Sausville E, Kim SH, Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2735-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8610110 8610110]
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Crystal structure of cyclin-dependent kinase 2., De Bondt HL, Rosenblatt J, Jancarik J, Jones HD, Morgan DO, Kim SH, Nature. 1993 Jun 17;363(6430):595-602. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8510751 8510751]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
 
[[Category: Jr., W F.De Azevedo.]]
[[Category: Jr., W F.De Azevedo.]]
[[Category: Kim, S H.]]
[[Category: Kim, S H.]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:56:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:34:01 2009''

Revision as of 03:34, 17 February 2009

Image:2a4l.png

Template:STRUCTURE 2a4l

Human cyclin-dependent kinase 2 in complex with roscovitine

Template:ABSTRACT PUBMED 9030780

About this Structure

2A4L is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur J Biochem. 1997 Jan 15;243(1-2):518-26. PMID:9030780
  • De Azevedo WF Jr, Mueller-Dieckmann HJ, Schulze-Gahmen U, Worland PJ, Sausville E, Kim SH. Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2735-40. PMID:8610110
  • De Bondt HL, Rosenblatt J, Jancarik J, Jones HD, Morgan DO, Kim SH. Crystal structure of cyclin-dependent kinase 2. Nature. 1993 Jun 17;363(6430):595-602. PMID:8510751 doi:http://dx.doi.org/10.1038/363595a0

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