2ntr

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==About this Structure==
==About this Structure==
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2NTR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTR OCA].
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2NTR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTR OCA].
==Reference==
==Reference==
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Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites., McGaughey GB, Colussi D, Graham SL, Lai MT, Munshi SK, Nantermet PG, Pietrak B, Rajapakse HA, Selnick HG, Stauffer SR, Holloway MK, Bioorg Med Chem Lett. 2007 Feb 15;17(4):1117-21. Epub 2006 Nov 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17112725 17112725]
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<ref group="xtra">PMID:17112725</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Single protein]]
 
[[Category: Munshi, S.]]
[[Category: Munshi, S.]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:16:02 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:49:47 2009''

Revision as of 03:49, 17 February 2009

Template:STRUCTURE 2ntr

Crystal structure of Human Bace-1 bound to inhibitor

Template:ABSTRACT PUBMED 17112725

About this Structure

2NTR is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McGaughey GB, Colussi D, Graham SL, Lai MT, Munshi SK, Nantermet PG, Pietrak B, Rajapakse HA, Selnick HG, Stauffer SR, Holloway MK. Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1117-21. Epub 2006 Nov 6. PMID:17112725 doi:10.1016/j.bmcl.2006.11.003

Page seeded by OCA on Tue Feb 17 05:49:47 2009

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