2i4j
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2I4J is a | + | 2I4J is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4J OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:17403688</ref><ref group="xtra">PMID:9744270</ref><ref group="xtra">PMID:10339548</ref><references group="xtra"/> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Mazza, F.]] | [[Category: Mazza, F.]] | ||
[[Category: Pochetti, G.]] | [[Category: Pochetti, G.]] | ||
[[Category: Bundle of alpha-helices and a small four-stranded beta-sheet]] | [[Category: Bundle of alpha-helices and a small four-stranded beta-sheet]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:53:25 2009'' |
Revision as of 05:53, 17 February 2009
Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)
Template:ABSTRACT PUBMED 17403688
About this Structure
2I4J is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pochetti G, Godio C, Mitro N, Caruso D, Galmozzi A, Scurati S, Loiodice F, Fracchiolla G, Tortorella P, Laghezza A, Lavecchia A, Novellino E, Mazza F, Crestani M. Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands. J Biol Chem. 2007 Jun 8;282(23):17314-24. Epub 2007 Apr 2. PMID:17403688 doi:10.1074/jbc.M702316200
- Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, Kurokawa R, Rosenfeld MG, Willson TM, Glass CK, Milburn MV. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature. 1998 Sep 10;395(6698):137-43. PMID:9744270 doi:10.1038/25931
- Oberfield JL, Collins JL, Holmes CP, Goreham DM, Cooper JP, Cobb JE, Lenhard JM, Hull-Ryde EA, Mohr CP, Blanchard SG, Parks DJ, Moore LB, Lehmann JM, Plunket K, Miller AB, Milburn MV, Kliewer SA, Willson TM. A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6102-6. PMID:10339548
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