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2pqz

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==About this Structure==
==About this Structure==
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2PQZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQZ OCA].
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2PQZ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQZ OCA].
==Reference==
==Reference==
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Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold., Blum A, Bottcher J, Heine A, Klebe G, Diederich WE, J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18348517 18348517]
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<ref group="xtra">PMID:18348517</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Single protein]]
 
[[Category: Blum, A.]]
[[Category: Blum, A.]]
[[Category: Boettcher, J.]]
[[Category: Boettcher, J.]]
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[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:04:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:39:59 2009''

Revision as of 06:40, 17 February 2009

Image:2pqz.png

Template:STRUCTURE 2pqz

HIV-1 Protease in complex with a pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18348517

About this Structure

2PQZ is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s

Page seeded by OCA on Tue Feb 17 08:39:59 2009

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