1xh4

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==About this Structure==
==About this Structure==
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1XH4 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XH4 OCA].
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1XH4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XH4 OCA].
==Reference==
==Reference==
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Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants., Breitenlechner CB, Friebe WG, Brunet E, Werner G, Graul K, Thomas U, Kunkele KP, Schafer W, Gassel M, Bossemeyer D, Huber R, Engh RA, Masjost B, J Med Chem. 2005 Jan 13;48(1):163-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15634010 15634010]
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<ref group="xtra">PMID:15634010</ref><ref group="xtra">PMID:14998327</ref><references group="xtra"/>
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Structure-based optimization of novel azepane derivatives as PKB inhibitors., Breitenlechner CB, Wegge T, Berillon L, Graul K, Marzenell K, Friebe WG, Thomas U, Schumacher R, Huber R, Engh RA, Masjost B, J Med Chem. 2004 Mar 11;47(6):1375-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14998327 14998327]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Protein complex]]
 
[[Category: Bossemeyer, D.]]
[[Category: Bossemeyer, D.]]
[[Category: Breitenlechner, C B.]]
[[Category: Breitenlechner, C B.]]
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:43:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:11:48 2009''

Revision as of 07:11, 17 February 2009

Image:1xh4.png

Template:STRUCTURE 1xh4

Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants

Template:ABSTRACT PUBMED 15634010

About this Structure

1XH4 is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Breitenlechner CB, Friebe WG, Brunet E, Werner G, Graul K, Thomas U, Kunkele KP, Schafer W, Gassel M, Bossemeyer D, Huber R, Engh RA, Masjost B. Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants. J Med Chem. 2005 Jan 13;48(1):163-70. PMID:15634010 doi:http://dx.doi.org/10.1021/jm049701n
  • Breitenlechner CB, Wegge T, Berillon L, Graul K, Marzenell K, Friebe WG, Thomas U, Schumacher R, Huber R, Engh RA, Masjost B. Structure-based optimization of novel azepane derivatives as PKB inhibitors. J Med Chem. 2004 Mar 11;47(6):1375-90. PMID:14998327 doi:http://dx.doi.org/10.1021/jm0310479

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