2ra0

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==About this Structure==
==About this Structure==
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2RA0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA0 OCA].
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2RA0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA0 OCA].
==Reference==
==Reference==
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7-fluoroindazoles as potent and selective inhibitors of factor Xa., Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR, J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18159923 18159923]
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<ref group="xtra">PMID:18159923</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Abad, M C.]]
[[Category: Abad, M C.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
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[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:01:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:26:31 2009''

Revision as of 07:26, 17 February 2009

Template:STRUCTURE 2ra0

Contents

X-ray Structure of FXa in complex with 7-fluoroindazole

Template:ABSTRACT PUBMED 18159923

Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

2RA0 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR. 7-fluoroindazoles as potent and selective inhibitors of factor Xa. J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:18159923 doi:10.1021/jm701217r

Page seeded by OCA on Tue Feb 17 09:26:31 2009

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