1o4j

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==About this Structure==
==About this Structure==
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1O4J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4J OCA].
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1O4J is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4J OCA].
==Reference==
==Reference==
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Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14613321 14613321]
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<ref group="xtra">PMID:14613321</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Lange, G.]]
[[Category: Lange, G.]]
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[[Category: Sh2 domain fragment approach]]
[[Category: Sh2 domain fragment approach]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:47:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:49:03 2009''

Revision as of 08:49, 17 February 2009

Template:STRUCTURE 1o4j

Contents

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH ISO24.

Template:ABSTRACT PUBMED 14613321

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1O4J is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

Page seeded by OCA on Tue Feb 17 10:49:03 2009

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