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2gtw

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==About this Structure==
==About this Structure==
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2GTW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTW OCA].
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2GTW is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTW OCA].
==Reference==
==Reference==
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Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition., Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM, J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17719062 17719062]
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<ref group="xtra">PMID:17719062</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Baker, B M.]]
[[Category: Baker, B M.]]
[[Category: Borbulevych, O Y.]]
[[Category: Borbulevych, O Y.]]
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[[Category: X-ray crystallography]]
[[Category: X-ray crystallography]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:23:02 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:19:02 2009''

Revision as of 09:19, 17 February 2009

Template:STRUCTURE 2gtw

Contents

Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution

Template:ABSTRACT PUBMED 17719062

Disease

Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[142800], Ankylosing spondylitis, susceptibility to, 1 OMIM:[142800], Stevens-Johnson syndrome, susceptibility to OMIM:[142800], Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

2GTW is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025

Page seeded by OCA on Tue Feb 17 11:19:02 2009

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