2hvx

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==About this Structure==
==About this Structure==
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2HVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVX OCA].
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2HVX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVX OCA].
==Reference==
==Reference==
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Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase., Greco MN, Hawkins MJ, Powell ET, Almond HR Jr, de Garavilla L, Hall J, Minor LK, Wang Y, Corcoran TW, Di Cera E, Cantwell AM, Savvides SN, Damiano BP, Maryanoff BE, J Med Chem. 2007 Apr 19;50(8):1727-30. Epub 2007 Mar 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17361995 17361995]
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<ref group="xtra">PMID:17361995</ref><references group="xtra"/>
[[Category: Chymase]]
[[Category: Chymase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Almond, H R]]
[[Category: Almond, H R]]
[[Category: Cantwell, A M.]]
[[Category: Cantwell, A M.]]
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[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:41:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:34:25 2009''

Revision as of 09:34, 17 February 2009

Template:STRUCTURE 2hvx

Discovery of Potent, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase by Using Structure-Based Drug Design

Template:ABSTRACT PUBMED 17361995

About this Structure

2HVX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Greco MN, Hawkins MJ, Powell ET, Almond HR Jr, de Garavilla L, Hall J, Minor LK, Wang Y, Corcoran TW, Di Cera E, Cantwell AM, Savvides SN, Damiano BP, Maryanoff BE. Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50(8):1727-30. Epub 2007 Mar 16. PMID:17361995 doi:10.1021/jm0700619

Page seeded by OCA on Tue Feb 17 11:34:25 2009

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