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2zmm
From Proteopedia
(Difference between revisions)
| Line 14: | Line 14: | ||
==Disease== | ==Disease== | ||
| - | Known disease associated with this structure: | + | Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]] |
==About this Structure== | ==About this Structure== | ||
| - | 2ZMM is a | + | 2ZMM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMM OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:18798205</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Wu, J.]] | [[Category: Wu, J.]] | ||
[[Category: Xu, W.]] | [[Category: Xu, W.]] | ||
| Line 37: | Line 36: | ||
[[Category: Ptp1b]] | [[Category: Ptp1b]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:47:15 2009'' |
Revision as of 10:47, 17 February 2009
Contents |
Crystal structure of PTP1B-inhibitor complex
Disease
Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[176885]
About this Structure
2ZMM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188
Page seeded by OCA on Tue Feb 17 12:47:15 2009
