1h8f

From Proteopedia

(Difference between revisions)

Revision as of 11:27, 17 February 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

Image:1h8f.png

1h8f, resolution 2.80Å ()

Ligands:

Activity:

Non-specific serine/threonine protein kinase, with EC number 2.7.11.1

Structural annotation:
Resources:	CATH : 1H8Fa02, 1H8Fa01, 1H8Fb02, 1H8Fb01 InterPro : Ipr011009, Ipr000719, Ipr008271, Ipr002290 Pfam : PF00069 SCOP : d1h8fa_, d1h8fb_ UniProt : P49841

Functional annotation:
Cellular component:	cytoplasm nucleus beta-catenin destruction complex
Biological process:	positive regulation of protein export from nucleus peptidyl-serine phosphorylation Wnt receptor signaling pathway through beta-catenin ER overload response Wnt receptor signaling pathway negative regulation of apoptosis protein amino acid phosphorylation intracellular signaling cascade glycogen metabolic process
Molecular function:	nucleotide binding ATP binding transferase activity p53 binding NF-kappaB binding kinase activity protein serine/threonine kinase activity protein kinase activity protein binding glycogen synthase kinase 3 activity

Evolutionary conservation:

Toggle Conservation Colors:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

GLYCOGEN SYNTHASE KINASE 3 BETA.

Template:ABSTRACT PUBMED 11440715

About this Structure

1H8F is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell. 2001 Jun 15;105(6):721-32. PMID:11440715

Page seeded by OCA on Tue Feb 17 13:27:19 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h8f"

@@ Line 20: / Line 20: @@
 ==About this Structure==
-H8F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8F OCA].
+H8F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8F OCA].
 ==Reference==
-Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition., Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH, Cell. 2001 Jun 15;105(6):721-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11440715 11440715]
+<ref group="xtra">PMID:11440715</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Non-specific serine/threonine protein kinase]]
-[[Category: Single protein]]
 [[Category: Dajani, R.]]
 [[Category: Pearl, L H.]]
@@ Line 33: / Line 32: @@
 [[Category: Kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 06:48:02 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:27:19 2009''

1h8f

From Proteopedia

Revision as of 11:27, 17 February 2009

GLYCOGEN SYNTHASE KINASE 3 BETA.

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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