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2auh

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==About this Structure==
==About this Structure==
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2AUH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUH OCA].
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2AUH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUH OCA].
==Reference==
==Reference==
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Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14., Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR, Mol Cell. 2005 Oct 28;20(2):325-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16246733 16246733]
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<ref group="xtra">PMID:16246733</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Daly, R J.]]
[[Category: Daly, R J.]]
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[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 3 10:35:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:39:19 2009''

Revision as of 11:39, 17 February 2009

Image:2auh.png

Template:STRUCTURE 2auh

Contents

Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase

Template:ABSTRACT PUBMED 16246733

Disease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]

About this Structure

2AUH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR. Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol Cell. 2005 Oct 28;20(2):325-33. PMID:16246733 doi:10.1016/j.molcel.2005.09.001

Page seeded by OCA on Tue Feb 17 13:39:19 2009

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