1h1b

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==About this Structure==
==About this Structure==
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1H1B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1B OCA].
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1H1B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1B OCA].
==Reference==
==Reference==
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Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)., Macdonald SJ, Dowle MD, Harrison LA, Clarke GD, Inglis GG, Johnson MR, Shah P, Smith RA, Amour A, Fleetwood G, Humphreys DC, Molloy CR, Dixon M, Godward RE, Wonacott AJ, Singh OM, Hodgson ST, Hardy GW, J Med Chem. 2002 Aug 29;45(18):3878-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12190311 12190311]
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<ref group="xtra">PMID:12190311</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Leukocyte elastase]]
[[Category: Leukocyte elastase]]
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[[Category: Single protein]]
 
[[Category: Amour, A.]]
[[Category: Amour, A.]]
[[Category: Clarke, G D.E.]]
[[Category: Clarke, G D.E.]]
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[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:27:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:51:55 2009''

Revision as of 12:51, 17 February 2009

Image:1h1b.png

Template:STRUCTURE 1h1b

CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE COMPLEXED WITH AN INHIBITOR (GW475151)

Template:ABSTRACT PUBMED 12190311

About this Structure

1H1B is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Macdonald SJ, Dowle MD, Harrison LA, Clarke GD, Inglis GG, Johnson MR, Shah P, Smith RA, Amour A, Fleetwood G, Humphreys DC, Molloy CR, Dixon M, Godward RE, Wonacott AJ, Singh OM, Hodgson ST, Hardy GW. Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151). J Med Chem. 2002 Aug 29;45(18):3878-90. PMID:12190311

Page seeded by OCA on Tue Feb 17 14:51:55 2009

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