2an3

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==About this Structure==
==About this Structure==
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2AN3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].
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2AN3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].
==Reference==
==Reference==
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Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis., Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL, Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16363801 16363801]
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<ref group="xtra">PMID:16363801</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]
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[[Category: Single protein]]
 
[[Category: Gee, C L.]]
[[Category: Gee, C L.]]
[[Category: Grunewald, G L.]]
[[Category: Grunewald, G L.]]
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[[Category: Substrate structure]]
[[Category: Substrate structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:51:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:00:50 2009''

Revision as of 15:00, 17 February 2009

Template:STRUCTURE 2an3

Contents

Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol.

Template:ABSTRACT PUBMED 16363801

Disease

Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[171190]

About this Structure

2AN3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:http://dx.doi.org/10.1021/bi051636b

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