2rda

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==About this Structure==
==About this Structure==
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2RDA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDA OCA].
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2RDA is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDA OCA].
==Reference==
==Reference==
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The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195., Gibson LM, Lovelace LL, Lebioda L, Biochemistry. 2008 Apr 22;47(16):4636-43. Epub 2008 Mar 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18370400 18370400]
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<ref group="xtra">PMID:18370400</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
[[Category: Gibson, L M.]]
[[Category: Gibson, L M.]]
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[[Category: Nucleotide biosynthesis]]
[[Category: Nucleotide biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:53:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:49:08 2009''

Revision as of 15:49, 17 February 2009

Template:STRUCTURE 2rda

Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195

Template:ABSTRACT PUBMED 18370400

About this Structure

2RDA is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gibson LM, Lovelace LL, Lebioda L. The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195. Biochemistry. 2008 Apr 22;47(16):4636-43. Epub 2008 Mar 28. PMID:18370400 doi:10.1021/bi7019386

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