Template:STRUCTURE 1d5r

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Revision as of 15:56, 17 February 2009

1d5r, resolution 2.10Å ()

Ligands:

Activity:

Protein-tyrosine-phosphatase, with EC number 3.1.3.48

Domains:

CDC14

Structural annotation:
Resources:	CATH : 1D5Ra02, 1D5Ra01 InterPro : Ipr014020, Ipr000340, Ipr000387, Ipr008973, Ipr000242, Ipr014019 Pfam : PF00782 SCOP : d1d5ra1, d1d5ra2 UniProt : P60484

Functional annotation:
Resources:	GeneCard : PTEN
Cellular component:	cytoplasm
Biological process:	phosphoinositide dephosphorylation induction of apoptosis cardiac muscle development cell migration heart development angiogenesis negative regulation of cell cycle regulation of protein stability dephosphorylation inositol phosphate dephosphorylation negative regulation of apoptosis cell cycle negative regulation of protein kinase B signaling cascade central nervous system development lipid metabolic process negative regulation of focal adhesion formation endothelial cell migration regulation of cyclin-dependent protein kinase activity cell proliferation negative regulation of cell migration protein amino acid dephosphorylation negative regulation of cell proliferation
Molecular function:	protein binding phosphoric monoester hydrolase activity lipid binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity PDZ domain binding protein tyrosine/serine/threonine phosphatase activity phosphoprotein phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity hydrolase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity protein tyrosine phosphatase activity protein serine/threonine phosphatase activity phosphatidylinositol-3-phosphatase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1d5r"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1d5r, resolution 2.10&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1d5r]], resolution 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
@@ Line 10: / Line 10: @@
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1d5rA02 1D5Ra02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1d5rA01 1D5Ra01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014020 Ipr014020], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000340 Ipr000340], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000387 Ipr000387], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008973 Ipr008973], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000242 Ipr000242], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014019 Ipr014019]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00782 PF00782]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=23181 d1d5ra1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=32697 d1d5ra2]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P60484 P60484]</span>
 |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=PTEN PTEN]</span>
+|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1d5r_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1d5r

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Revision as of 15:56, 17 February 2009

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