3ch6

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==About this Structure==
==About this Structure==
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3CH6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CH6 OCA].
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3CH6 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CH6 OCA].
==Reference==
==Reference==
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Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1., Wang H, Ruan Z, Li JJ, Simpkins LM, Smirk RA, Wu SC, Hutchins RD, Nirschl DS, Van Kirk K, Cooper CB, Sutton JC, Ma Z, Golla R, Seethala R, Salyan ME, Nayeem A, Krystek SR Jr, Sheriff S, Camac DM, Morin PE, Carpenter B, Robl JA, Zahler R, Gordon DA, Hamann LG, Bioorg Med Chem Lett. 2008 Jun 1;18(11):3168-72. Epub 2008 May 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18485702 18485702]
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<ref group="xtra">PMID:18485702</ref><references group="xtra"/>
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Sheriff, S.]]
[[Category: Sheriff, S.]]
[[Category: 11b-hsd1]]
[[Category: 11b-hsd1]]
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[[Category: Sdr]]
[[Category: Sdr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:08:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:03:51 2009''

Revision as of 16:03, 17 February 2009

Template:STRUCTURE 3ch6

Crystal Structure of 11beta-HSD1 Double Mutant (L262R, F278E) Complexed with (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone

Template:ABSTRACT PUBMED 18485702

About this Structure

3CH6 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang H, Ruan Z, Li JJ, Simpkins LM, Smirk RA, Wu SC, Hutchins RD, Nirschl DS, Van Kirk K, Cooper CB, Sutton JC, Ma Z, Golla R, Seethala R, Salyan ME, Nayeem A, Krystek SR Jr, Sheriff S, Camac DM, Morin PE, Carpenter B, Robl JA, Zahler R, Gordon DA, Hamann LG. Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3168-72. Epub 2008 May 1. PMID:18485702 doi:http://dx.doi.org/10.1016/j.bmcl.2008.04.069

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