1t4v
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 1T4V is a | + | 1T4V is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4V OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15203151</ref><references group="xtra"/> | |
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Spurlino, J.]] | [[Category: Spurlino, J.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:36:48 2009'' |
Revision as of 16:36, 17 February 2009
Contents |
Crystal Structure Analysis of a novel Oxyguanidine bound to Thrombin
Template:ABSTRACT PUBMED 15203151
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1T4V is a 3 chains structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lu T, Markotan T, Coppo F, Tomczuk B, Crysler C, Eisennagel S, Spurlino J, Gremminger L, Soll RM, Giardino EC, Bone R. Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3727-31. PMID:15203151 doi:http://dx.doi.org/10.1016/j.bmcl.2004.05.002
Page seeded by OCA on Tue Feb 17 18:36:48 2009
