2rgp

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[[Image:2rgp.jpg|left|200px]]
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==About this Structure==
==About this Structure==
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2RGP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGP OCA].
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2RGP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGP OCA].
==Reference==
==Reference==
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4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors., Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18653333 18653333]
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<ref group="xtra">PMID:18653333</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
 
[[Category: Abad, M C.]]
[[Category: Abad, M C.]]
[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
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[[Category: Ubl conjugation]]
[[Category: Ubl conjugation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:09:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:03:42 2009''

Revision as of 17:03, 17 February 2009

Image:2rgp.png

Template:STRUCTURE 2rgp

Structure of EGFR in complex with hydrazone, a potent dual inhibitor

Template:ABSTRACT PUBMED 18653333

About this Structure

2RGP is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA. 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333 doi:10.1016/j.bmcl.2008.07.020

Page seeded by OCA on Tue Feb 17 19:03:42 2009

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