1ia4
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 1IA4 is a | + | 1IA4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA4 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:11520201</ref><references group="xtra"/> | |
[[Category: Candida albicans]] | [[Category: Candida albicans]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Howard, A J.]] | [[Category: Howard, A J.]] | ||
[[Category: Kuyper, L F.]] | [[Category: Kuyper, L F.]] | ||
| Line 35: | Line 34: | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:05:45 2009'' |
Revision as of 17:05, 17 February 2009
Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOLINEDIAMIN (GW2021)
Template:ABSTRACT PUBMED 11520201
About this Structure
1IA4 is a 2 chains structure of sequences from Candida albicans. Full crystallographic information is available from OCA.
Reference
- Whitlow M, Howard AJ, Stewart D, Hardman KD, Chan JH, Baccanari DP, Tansik RL, Hong JS, Kuyper LF. X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. J Med Chem. 2001 Aug 30;44(18):2928-32. PMID:11520201
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