2fji
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(New page: 200px<br /><applet load="2fji" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fji, resolution 2.40Å" /> '''Crystal structure of...)
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Revision as of 08:27, 21 November 2007
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Crystal structure of the C-terminal domain of the exocyst subunit Sec6p
Overview
The exocyst is a conserved protein complex essential for trafficking, secretory vesicles to the plasma membrane. The structure of the C-terminal, domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the, C-terminal domains of Exo84p and Sec15, despite <10% sequence identity., The helical bundles appear to be evolutionarily related molecular, scaffolds that have diverged to create functionally distinct exocyst, proteins.
About this Structure
2FJI is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles., Sivaram MV, Furgason ML, Brewer DN, Munson M, Nat Struct Mol Biol. 2006 Jun;13(6):555-6. Epub 2006 May 14. PMID:16699513
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