2fw3

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(New page: 200px<br /><applet load="2fw3" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fw3, resolution 2.50&Aring;" /> '''Crystal structure of...)
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Revision as of 08:41, 21 November 2007

Image:2fw3.gif

2fw3, resolution 2.50Å

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Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326

Overview

Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system, that imports fatty acids into mitochondria. The crystal structure of rat, CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped, tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic, insert mediating membrane association.

About this Structure

2FW3 is a Single protein structure of sequence from Rattus norvegicus with BUI as ligand. Active as Carnitine O-palmitoyltransferase, with EC number 2.3.1.21 Full crystallographic information is available from OCA.

Reference

A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901

Page seeded by OCA on Wed Nov 21 10:48:22 2007

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