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2i1m

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==About this Structure==
==About this Structure==
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2I1M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1M OCA].
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2I1M is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1M OCA].
==Reference==
==Reference==
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Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors., Schubert C, Schalk-Hihi C, Struble GT, Ma HC, Petrounia IP, Brandt B, Deckman IC, Patch RJ, Player MR, Spurlino JC, Springer BA, J Biol Chem. 2007 Feb 9;282(6):4094-101. Epub 2006 Nov 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17132624 17132624]
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<ref group="xtra">PMID:17132624</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
 
[[Category: Schalk-Hihi, C.]]
[[Category: Schalk-Hihi, C.]]
[[Category: Schubert, C.]]
[[Category: Schubert, C.]]
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[[Category: Kinase inhibitor complex]]
[[Category: Kinase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:10:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:57:30 2009''

Revision as of 19:57, 17 February 2009

Template:STRUCTURE 2i1m

Contents

cFMS tyrosine kinase (tie2 KID) in complex with an arylamide inhibitor

Template:ABSTRACT PUBMED 17132624

Disease

Known disease associated with this structure: Myeloid malignancy, predisposition to OMIM:[164770]

About this Structure

2I1M is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schubert C, Schalk-Hihi C, Struble GT, Ma HC, Petrounia IP, Brandt B, Deckman IC, Patch RJ, Player MR, Spurlino JC, Springer BA. Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors. J Biol Chem. 2007 Feb 9;282(6):4094-101. Epub 2006 Nov 28. PMID:17132624 doi:http://dx.doi.org/10.1074/jbc.M608183200

Page seeded by OCA on Tue Feb 17 21:57:30 2009

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