2hx2

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==About this Structure==
==About this Structure==
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2HX2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX2 OCA].
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2HX2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX2 OCA].
==Reference==
==Reference==
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Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water., Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB, J Med Chem. 2007 May 3;50(9):2089-99. Epub 2007 Apr 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17425297 17425297]
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<ref group="xtra">PMID:17425297</ref><ref group="xtra">PMID:14718923</ref><references group="xtra"/>
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+
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Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase., Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL, Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14718923 14718923]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
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[[Category: Single protein]]
 
[[Category: Igarashi, J.]]
[[Category: Igarashi, J.]]
[[Category: Li, H.]]
[[Category: Li, H.]]
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[[Category: Nitric oxide synthase]]
[[Category: Nitric oxide synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:13:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:56:55 2009''

Revision as of 21:56, 17 February 2009

Template:STRUCTURE 2hx2

Bovine eNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine

Template:ABSTRACT PUBMED 17425297

About this Structure

2HX2 is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. J Med Chem. 2007 May 3;50(9):2089-99. Epub 2007 Apr 11. PMID:17425297 doi:10.1021/jm061305c
  • Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:14718923 doi:http://dx.doi.org/10.1038/nsmb704

Page seeded by OCA on Tue Feb 17 23:56:55 2009

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