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2f3f

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==About this Structure==
==About this Structure==
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2F3F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3F OCA].
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2F3F is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3F OCA].
==Reference==
==Reference==
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Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE)., Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M, J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16854060 16854060]
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<ref group="xtra">PMID:16854060</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Single protein]]
 
[[Category: Rondeau, J M.]]
[[Category: Rondeau, J M.]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
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[[Category: Memapsin2]]
[[Category: Memapsin2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:36:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:15:20 2009''

Revision as of 22:15, 17 February 2009

Template:STRUCTURE 2f3f

Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor

Template:ABSTRACT PUBMED 16854060

About this Structure

2F3F is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060 doi:10.1021/jm060154a

Page seeded by OCA on Wed Feb 18 00:15:20 2009

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