3bva

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==About this Structure==
==About this Structure==
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3BVA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVA OCA].
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3BVA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVA OCA].
==Reference==
==Reference==
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Effect of the active-site D25N mutation on the structure, stability and ligand binding of the mature HIV-1 protease., Sayer JM, Liu F, Ishima R, Weber IT, Louis JM, J Biol Chem. 2008 Feb 15;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18281688 18281688]
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<ref group="xtra">PMID:18281688</ref><ref group="xtra">PMID:12933791</ref><ref group="xtra">PMID:16277992</ref><references group="xtra"/>
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Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor., Ishima R, Torchia DA, Lynch SM, Gronenborn AM, Louis JM, J Biol Chem. 2003 Oct 31;278(44):43311-9. Epub 2003 Aug 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12933791 12933791]
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Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S., Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16277992 16277992]
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[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Single protein]]
 
[[Category: Liu, F.]]
[[Category: Liu, F.]]
[[Category: Weber, I T.]]
[[Category: Weber, I T.]]
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[[Category: Mutation]]
[[Category: Mutation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:51:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:59:46 2009''

Revision as of 23:59, 17 February 2009

Image:3bva.png

Template:STRUCTURE 3bva

Cystal structure of HIV-1 Active Site Mutant D25N and p2-NC analog inhibitor

Template:ABSTRACT PUBMED 18281688

About this Structure

3BVA is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Sayer JM, Liu F, Ishima R, Weber IT, Louis JM. Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease. J Biol Chem. 2008 May 9;283(19):13459-70. Epub 2008 Feb 15. PMID:18281688 doi:10.1074/jbc.M708506200
  • Ishima R, Torchia DA, Lynch SM, Gronenborn AM, Louis JM. Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem. 2003 Oct 31;278(44):43311-9. Epub 2003 Aug 21. PMID:12933791 doi:http://dx.doi.org/10.1074/jbc.M307549200
  • Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095

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