2dqu

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==About this Structure==
==About this Structure==
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This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hyy 1hyy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQU OCA].
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2DQU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hyy 1hyy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQU OCA].
==Reference==
==Reference==
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Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis., Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I, J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17428500 17428500]
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<ref group="xtra">PMID:17428500</ref><ref group="xtra">PMID:9150409</ref><ref group="xtra">PMID:7938025</ref><ref group="xtra">PMID:8016113</ref><ref group="xtra">PMID:8506382</ref><references group="xtra"/>
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[[Category: Mus musculus]]
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Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization., Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A, Fujii I, J Mol Biol. 1997 Apr 18;267(5):1247-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9150409 9150409]
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A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10757. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7938025 7938025]
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A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6045-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8016113 8016113]
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Prodrug activation via catalytic antibodies., Miyashita H, Karaki Y, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5337-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8506382 8506382]
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[[Category: Fujii, I.]]
[[Category: Fujii, I.]]
[[Category: Ito, N.]]
[[Category: Ito, N.]]
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[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:34:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:53:51 2009''

Revision as of 00:53, 18 February 2009

Image:2dqu.png

Template:STRUCTURE 2dqu

Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog

Template:ABSTRACT PUBMED 17428500

About this Structure

2DQU is a 2 chains structure of sequences from Mus musculus. This structure supersedes the now removed PDB entry 1hyy. Full crystallographic information is available from OCA.

Reference

  • Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I. Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis. J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:17428500 doi:10.1016/j.jmb.2007.03.023
  • Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A, Fujii I. Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization. J Mol Biol. 1997 Apr 18;267(5):1247-57. PMID:9150409 doi:10.1006/jmbi.1997.0938
  • Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I. A common ancestry for multiple catalytic antibodies generated against a single transition-state analog. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10757. PMID:7938025
  • Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M, Fujii I. A common ancestry for multiple catalytic antibodies generated against a single transition-state analog. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6045-9. PMID:8016113
  • Miyashita H, Karaki Y, Kikuchi M, Fujii I. Prodrug activation via catalytic antibodies. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5337-40. PMID:8506382

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