2q15
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 2Q15 is a | + | 2Q15 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q15 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:17685503</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Sharff, A J.]] | [[Category: Sharff, A J.]] | ||
[[Category: Bace inhibitor complex]] | [[Category: Bace inhibitor complex]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:10:34 2009'' |
Revision as of 03:10, 18 February 2009
Structure of BACE complexed to compound 3a
Template:ABSTRACT PUBMED 17685503
About this Structure
2Q15 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Baxter EW, Conway KA, Kennis L, Bischoff F, Mercken MH, Winter HL, Reynolds CH, Tounge BA, Luo C, Scott MK, Huang Y, Braeken M, Pieters SM, Berthelot DJ, Masure S, Bruinzeel WD, Jordan AD, Parker MH, Boyd RE, Qu J, Alexander RS, Brenneman DE, Reitz AB. 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead. J Med Chem. 2007 Sep 6;50(18):4261-4. Epub 2007 Aug 8. PMID:17685503 doi:10.1021/jm0705408
Page seeded by OCA on Wed Feb 18 05:10:34 2009
