1py5
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 1PY5 is a | + | 1PY5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY5 OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:15177479</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
- | [[Category: Single protein]] | ||
[[Category: Sawyer, J S.]] | [[Category: Sawyer, J S.]] | ||
[[Category: Zhang, F.]] | [[Category: Zhang, F.]] | ||
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[[Category: Tgf-beta]] | [[Category: Tgf-beta]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:31:12 2009'' |
Revision as of 03:31, 18 February 2009
Contents |
Crystal Structure of TGF-beta receptor I kinase with inhibitor
Template:ABSTRACT PUBMED 15177479
Disease
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this Structure
1PY5 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sawyer JS, Beight DW, Britt KS, Anderson BD, Campbell RM, Goodson T Jr, Herron DK, Li HY, McMillen WT, Mort N, Parsons S, Smith EC, Wagner JR, Yan L, Zhang F, Yingling JM. Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3581-4. PMID:15177479 doi:http://dx.doi.org/10.1016/j.bmcl.2004.04.007
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