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1nh3

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==About this Structure==
==About this Structure==
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1NH3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NH3 OCA].
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1NH3 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NH3 OCA].
==Reference==
==Reference==
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Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex., Chrencik JE, Burgin AB, Pommier Y, Stewart L, Redinbo MR, J Biol Chem. 2003 Apr 4;278(14):12461-6. Epub 2003 Jan 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12533542 12533542]
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<ref group="xtra">PMID:12533542</ref><references group="xtra"/>
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Burgin, A B.]]
[[Category: Burgin, A B.]]
[[Category: Chrencik, J E.]]
[[Category: Chrencik, J E.]]
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[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:16:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:33:33 2009''

Revision as of 03:33, 18 February 2009

Image:1nh3.png

Template:STRUCTURE 1nh3

Contents

Human Topoisomerase I Ara-C Complex

Template:ABSTRACT PUBMED 12533542

Disease

Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]

About this Structure

1NH3 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chrencik JE, Burgin AB, Pommier Y, Stewart L, Redinbo MR. Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex. J Biol Chem. 2003 Apr 4;278(14):12461-6. Epub 2003 Jan 17. PMID:12533542 doi:10.1074/jbc.M212930200

Page seeded by OCA on Wed Feb 18 05:33:33 2009

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